WebFeb 4, 2024 · ChIP analysis showed that TET3 knockdown significantly decreased H3K4me3 (Figure 2D, left columns) and increased H3K27me3 (middle columns) association with the CTRRs of TSP1 and TGFBR2, … WebJan 17, 2024 · Fig. 5 TET3 interacts with FOXA2. a TET3 ChIP-qPCR of mouse primary hepatocytes infected with AAV-scr or AAV-siFOXA2 for 48 h, followed by glucagon (20 nM) stimulation for 48 h. n = 3, one-way ...
TET2 and TET3 regulate GlcNAcylation and H3K4 …
WebApr 12, 2024 · TET proteins, particularly TET2 and TET3, have critical roles in B cell differentiation and malignancy ().We and others have previously shown that deletion of Tet2 and Tet3 at early stages of mouse B cell development with an Mb1-Cre transgene resulted in impaired light-chain rearrangement and developmental blockade, leading to acute … WebFeb 24, 2024 · 进行cetsa,分析iox1与jmjd3、kdm3a、kem4e(d)之间以及iox1与tet2、tet3(e)之间的潜在缔合。 ... 而且,chip分析证明,tet2直接与il17a启动子的cpg-6-8位点结合,而chem-ip分析(图8a示出了生物素化的iox1的化学结构)表明iox1也与il17a启动子 … small dog clipart black and white
TET3 interacts with FOXA2 a TET3 ChIP-qPCR of mouse
WebTET3 interacts with FOXA2 a TET3 ChIP-qPCR of mouse primary hepatocytes infected with AAV-scr or AAV-siFOXA2 for 48 h, followed by glucagon (20 nM) stimulation for 48 h. n = 3, one-way ANOVA with ... WebTet2- and Tet3-deficient B cells had decreased accumulation of histone deacetylase 1 (HDAC1) and HDAC2 at the Cd86 locus. Thus, our findings suggest that Tet2- and Tet3-mediated chromatin modification participates in repression of CD86 on chronically stimulated self-reactive B cells, which contributes, at least in part, to preventing autoimmunity. WebThis ChIP-seq protocol details our procedure to analyze TET2 bound DNA in disuccinimidyl glutarate (DSG) and formaldehyde-crosslinked chromatin but can also be adapted to … small dog christmas sweaters