WebNov 14, 2014 · The inhalation NOAEL was 0.167 mg/L for glycerin administered for 5 h/day, 5 days/week for 13 weeks in rats. No adverse effects were observed in rats administered 20% glycerin in drinking water throughout gestation and nursing of pups. The F 1 generation reproduced normally. http://www.cir-safety.org/sites/default/files/glycerin.pdf
Provisional Peer-Reviewed Toxicity Values for Triacetin …
The highest dose levels ranged from 1180 mg/kg/day in rabbits to 1310 mg/kg/day in rats. No additional relevant studies were summarised by any of the official bodies (MAK 2007 and 2016, OECD 2002, EFSA 2024). The overall conclusion was that there was no evidence of teratogenicity for glycerol. All NOAEL values … See more ECHA’s goal is to maintain this ECHA website and any information on this ECHA website available, accurate, up-to-date and functioning. However, ECHA makes no representations or … See more The User shall not transmit to, from or via the ECHA website, or post on the ECHA website any material which could be unlawful, harmful, … See more In addition to the publication of general information related to its operational activities or otherwise, ECHA publishes the authentic versions of the following lists and information on the ECHA website: 1. The Candidate List … See more WebThe greatest concentration or amount of a substance at which no detectable adverse effects occur in an exposed population. change windows to go startup options
What Is Benchmark Dose (BMD) and How to Calculate BMDL
WebDec 1, 2024 · PG is commonly used as a solvent in preclinical studies and the reported NOAEL for rat is 2 g/kg and used as a co-solvent in parenteral formulations in the range of 10–60% (EMA, 2014). ... LD50 of ethanol, diethylacetamide, dimethylformamide, dimethylsulfoxide, glycerine, N-methylpyrrolidone, polyethylene glycol 400, 1, 2 … WebGlycerin is a clear, syrupy liquid (Table 1).2,6 It can be in a crystallized state, but seldom is because of its tendency to supercool and the pronounced effect of small amounts of … WebGlycerin 56-81-5 Bioaccumulative potential. Non-bioaccumulative. Chemical name CAS No. Octanol/water partition coefficient Bioconcentration factor (BCF) Glycerin 56-81-5 -1.75 Mobility. Chemical name CAS No. log Koc Dissociation constant (Henry) Glycerin 56-81-5 Calculation. Result: 0.000000006 atm m3/mol@25 °C Other adverse effects No ... change windows update time