Phospho dap12 antibody
WebRabbit polyclonal antibody raised against synthetic phosphopeptide of ABL1/ABL2. Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y393/Y429 of human ABL1/ABL2. (PAB12190) - Products - Abnova WebPhosphospecific antibodies are affinity-purified rabbit polyclonal or monoclonal antibodies that are monospecific for a target protein that is phosphorylated. These antibodies provide critical insight into the investigation of complex signal transductions events. On this page Why use phosphospecific antibodies?
Phospho dap12 antibody
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WebJun 21, 2024 · Ligation of a DAP12-associated receptor to its ligand leads to the activation of SRC-family kinases and subsequent phosphorylation of tyrosine residues in the ITAM of DAP12 ( Mason et al., 2006 ). DAP12 was originally shown to trigger the activation of NK cells ( Lanier et al., 1998 ). WebPhosphospecific antibodies are affinity-purified rabbit polyclonal or monoclonal antibodies that are monospecific for a target protein that is phosphorylated. These antibodies …
WebOverall our data show that TREM2/DAP12 anti-inflammatory activity is mediated by signaling events distinct from those required to mediate TREM2 dependent phagocytic activity. In addition, we show that TREM2 … WebHuman DAP12 Antibody Summary Species Reactivity Human Specificity Detects human DAP12 in Western blots. Source Monoclonal Mouse IgG 1 Clone # 406288 Purification Protein A or G purified from hybridoma culture supernatant Immunogen Human Dap12 synthetic peptide QGQRSDVYSDLNTQRPYYK Accession # O43914 Formulation
WebFeb 12, 1998 · Here we show that DAP12, a disulphide-bonded homodimer containing an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain, non … WebThis product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free production For …
WebView Human DAP12 Alexa Fluor® 647-conjugated Antibody (FAB52401R-100UG) datasheet. Skip to main content. 0 Items; Products . Products by Category ... Human Phospho-SLP-76/LCP2 (Y145) Antibody. Cat # MAB7474. MitoBrilliant™ Live 549. Cat # 7693. Human CD14 Antibody. Cat # MAB11245. Se-NADA. Cat # 7449. MitoMark Green I. Cat # 6444 ...
WebAug 14, 2024 · AL002a promoted TREM2-dependent DAP12 and Syk phosphorylation. Panel a shows that AL002a binds to BMM derived from WT, but not Trem2 KO mice, as measured by FACS. A rat anti-Trem2 antibody from R&D Systems was used as a positive binding control and an isotype msIgG1 antibody as a negative control. chunky loafers with gold chainWebDec 27, 2024 · DAP12 is a phosphoprotein that is involved in the activation of NK cells. This protein interacts with membrane glycoproteins of the KIR family, resulting in cellular … chunky loafers with gold buckleWebDAP12, also known as TYROBP and KARAP, is a transmembrane protein that functions as a signal transduction adaptor molecule. DAP12 is expressed as a disulfide-linked homodimer that associates with a variety of receptors on NK and myeloid cells. Complex formation is mediated by intramembrane ionic interaction between an aspartic acid residue in ... chunky loafers women outfitsWebJun 18, 2024 · Microglia plays crucial roles in Alzheimer’s disease (AD) development. Triggering receptor expressed on myeloid cells 2 (TREM2) in association with DAP12 mediates signaling affecting microglia function. Here we study the negative regulation of TREM2 functions by leukocyte immunoglobulin-like receptor subfamily B member 2 … determine 22 1/2% of 80WebJun 17, 2014 · Generation anti-CD160-TMspecific antibodies Two rabbits were immunized peptideslocated within Ig-likedomain (peptide SSASQEGTRLNLIC,aminoacids 31-44) membrane-proximalregion (peptide KQRQHLEFSHNNEGTL,aminoacids 144-158) bothCD160 CD160-TMextracellular part. determine 30 40 45 and 60 are in proportionDNAX-activating protein 12 (DAP12, TYROBP) is a signaling adaptor for several pathogen receptors expressed by cells of the innate immune system (1). The DAP12 protein structure consists of a short extracellular domain, a transmembrane domain, and a cytoplasmic immunoreceptor tyrosine-based activation motif (ITAM) (2). chunky loafers with skinny jeansWeb纤粘连蛋白CAS号：86088-83-7 英文名称：Fibronectin from human plasma；CIG；Cold insoluble globulin 其他名称：纤连蛋白(人血)；纤链蛋白；粘连蛋白；纤维结合素；血清纤维结合蛋白 chunky loafer women