Rab gtpase-activating protein
WebAbstract. When the bacterium Legionella pneumophila, the causative agent of Legionnaires' disease, is phagocytosed by alveolar macrophages, it delivers a large number of effector … WebTBC1D5 functions as a GTPase-activating protein for RAB7 and inhibits recruitment of the VPS35/VPS29/VPS26 subcomplex to membranes (Seaman et al., 2009). ... Membrane …
Rab gtpase-activating protein
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WebMar 21, 2024 · RABGAP1L (RAB GTPase Activating Protein 1 Like) is a Protein Coding gene. Diseases associated with RABGAP1L include Cholesteatoma Of Middle Ear . Gene … WebThe Rab GTPase-activating protein TBC1D4/AS160 regulates GLUT4 trafficking in adipocytes. Nonphosphorylated AS160 binds to GLUT4 vesicles and inhibits GLUT4 …
WebOct 5, 2016 · Sendes innen 6-16 virkedager. Kjøp boken Rab GTPases (ISBN 9781493955947) hos Adlibris.com. Fri frakt. Vi har mer enn 10 millioner bøker, finn din … WebFeb 8, 2024 · Rab GTPase activating proteins (RabGAPs) with a Tre-2/Bub2/Cdc16 (TBC) domain is associated with membrane-bound compartments and autophagy . RabGAP …
WebThe conserved 1,030-amino acid protein has a calculated molecular mass of 118 kD. It contains a phosphotyrosine interaction domain, 2 PEST sequences, and several potential … GTPase-activating proteins or GTPase-accelerating proteins (GAPs) are a family of regulatory proteins whose members can bind to activated G proteins and stimulate their GTPase activity, with the result of terminating the signaling event. GAPs are also known as RGS protein, or RGS proteins, and these proteins are crucial in controlling the activity of G proteins. Regulation of G proteins is important because these proteins are involved in a variety of important cellular processes. The l…
WebJun 11, 2007 · In this study, we have investigated which Rab GTPase-activating proteins (GAPs) can interfere with the trafficking of Shiga toxin from the cell surface to the Golgi …
WebThe promoter activity of Rab4 was increased by metformin in an AMPK-dependent manner. Metformin stimulated the phosphorylation of AS160, Akt substrate, and Rab GTPase … allstate 60004WebSpecifically, I identified the activating accessory protein (GEF) for a highly conserved Rab GTPase necessary for LRO formation using a genetic bypass approach. allstate 60629WebGTPase-activating protein; Rab GTPase; Effector protein; Download protocol PDF Springer Nature is developing a new tool to find and evaluate Protocols. Learn more. 1 … allstate 60607WebSep 10, 2024 · Rab proteins are small GTPases that act as molecular switches for intracellular vesicle trafficking. Although their function is mainly regulated by regulatory … allstate 60632WebNotably, Rab GTPases can be involved in tumour cell migration, invasion, proliferation, stromal cell communication, and drug resistance. 8 The activity of Rab GTPases can be … allstate 60462WebJan 1, 2024 · 1. Introduction. Small GTPase family is a GTP-binding protein family which can be commonly found in eukaryotic cells [1].It is a kind of GTPases can achieve mutual transformation between GTP and GDP in cytoplasm [2].These small GTPases act as molecular switches in cells, affecting almost all cellular processes [3].The most … allstate 60619WebAug 15, 2012 · The Rab-GTPase-activating protein TBC1D1 has emerged as a novel candidate involved in metabolic regulation. Our aim was to determine whether TBC1D1 is … allstate 62025